Isonicotinic acid, 3-amino-, ethyl ester (8CI)

Isonicotinic acid, 3-amino-, ethyl ester (8CI) - Names and Identifiers

Name	3-AMINO-ISONICOTINIC ACID ETHYL ESTER
Synonyms	Ethyl 3-Aminoisonicotinate Ethyl3-amino-4-pyridinecarboxylate ethyl 3-aMinopyridin-4-carboxylate ETHYL 3-AMINOPYRIDINE-4-CARBOXYLATE 3-Amino-isonicotinic acid ethyl ester 3-AMINO-ISONICOTINIC ACID ETHYL ESTER 3-AMINO-4-PYRIDINECARBOXYLIC ACID ETHYL ESTER 3-AMINOPYRIDINE-4-CARBOXYLIC ACID ETHYL ESTER Isonicotinic acid, 3-amino-, ethyl ester (8CI) Ethyl 3-aminopyridine-4-carboxylate, 4-(Ethoxycarbonyl)pyridin-3-amine
CAS	14208-83-4
InChI	InChI=1/C8H10N2O2/c1-2-12-8(11)6-3-4-10-5-7(6)9/h3-5H,2,9H2,1H3

Isonicotinic acid, 3-amino-, ethyl ester (8CI) - Physico-chemical Properties

Molecular Formula	C8H10N2O2
Molar Mass	166.18
Density	1.192±0.06 g/cm3(Predicted)
Melting Point	170-175
Boling Point	304.0±22.0 °C(Predicted)
Flash Point	137.645°C
Vapor Presure	0.001mmHg at 25°C
Appearance	Solid
pKa	4.13±0.18(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.559
MDL	MFCD03788270

Isonicotinic acid, 3-amino-, ethyl ester (8CI) - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
HS Code	29339900
Hazard Note	Irritant

Isonicotinic acid, 3-amino-, ethyl ester (8CI) - Introduction

Ethyl 3-aminopyridine-4-carboxylate is a chemical substance whose molecular formula is C8H10N2O2.

Its properties are as follows:
1. appearance: colorless or yellowish oily liquid.
2. Solubility: Soluble in common organic solvents, such as ethanol, ether, etc.
3. Stability: relatively stable at room temperature, but it will decompose when encountering strong acid or alkali.

3-aminopyridine-4-carboxylic acid ethyl ester is mainly used in the carboxylation reaction in organic synthesis. It can be used as a substrate to react with acid or anhydride to generate the corresponding carboxylic acid compound. Its main application areas include drug synthesis, dye synthesis and so on.

There are many methods for preparing 3-aminopyridine-4-carboxylic acid ethyl ester, and the commonly used method is the esterification reaction of 3-aminopyridine and dimethylcarbamic acid ethyl ester.

in the use of 3-aminopyridine-4-carboxylic acid ethyl ester to pay attention to some safety matters:
1. Avoid contact with skin and eyes. If there is contact, rinse immediately with plenty of water.
2. Avoid inhaling its vapor and ensure that it is operated in a well-ventilated place.
3. storage should be sealed, away from heat and fire sources.

Last Update：2024-04-09 02:00:42